The synthesis of o-chloronitrobenzene and o-nitro aniline diphenylamine as a model to investigate the best conditions for coupling reaction of carbon and nitrogen. The reaction conditions are: at 190 ℃, will excessive nitrochlorobenzene into aniline and alkali sodium bicarbonate solution, with the PEG-800 as the catalyst for 24 hours, and then re-crystallized products. In which the molar ratio of each substance nitrochlorobenzene: aniline: PEG-800: NaHCO3 = 1:2:0.12:0.55, the resulting yield was 80.3%. Determined by IR structure of the product, the product of the capillary melting point determination, using liquid chromatography analysis of product purity and content. By measuring, determine the best carbon and nitrogen coupling reaction conditions. The reaction is simple, raw materials, low cost, mild reaction conditions, can be applied to industrial production.
O Nitrodiphenylamine nitrochlorobenzene and by the reaction of aniline
Halogenated aromatic nucleophilic substitution reactions of the general formula
Nitrochlorobenzene with aniline as a model of the CN coupling reaction
Schematic vertical cylinder chromatography
Rf value of the measurement method
TLC method trace the reaction process
IR spectra of the product
High performance liquid chromatogram of the product
Catalysts on the yield of
Amount of catalyst on product yield
The choice of acid binding agents on the product yield
Acid binding agent dosage on the reaction yield
Raw materials ratio on the yield of
Reaction temperature on the yield of
追问这是用林格斯翻译的吧！ 我有的，呵呵~